AI is transforming cybersecurity and the threat landscape at the same time. The same machine-learning systems that speed up threat detection and automate response are now prime targets for adversaries, who use generative AI to craft flawless phishing, clone voices, and manipulate the models themselves. In 2025 this shift became impossible to ignore: roughly 87% of organizations reported facing AI-driven attacks, and the FBI's 2025 Internet Crime Report created a dedicated AI crime category for the first time, logging 22,364 complaints and $893 million in confirmed losses.
Securing AI is now a regulatory obligation as well as a technical one. The EU AI Act's obligations for general-purpose AI (GPAI) models took effect on 2 August 2025, and the OWASP Top 10 for LLM Applications 2025 gives security teams a shared vocabulary for the highest-risk generative-AI failures, led by prompt injection. This guide explains the convergence of AI and cybersecurity, walks through the key threats targeting AI systems, and lays out practical, current best practices—grounded in the latest standards, regulations, and research—so you can protect the data and operations AI manages.
